Resinoid of Canarium luzonicum (Burseraceae) obtained from the exudate by cyclohexane extraction

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

19-20 February 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The study was conducted according to an internationally recognised method, and under GLP. The test substance is adequately characterised. Therefore full validation applies.

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2008

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

Inspected on 13 and 14 October 2014/ Signed on 8 April 2015

Type of method:

method according to Siwoloboff

Key result

Boiling pt.:

202.5 °C

Atm. press.:

>= 99 734 - <= 99 760 Pa

Decomposition:

yes

Decomp. temp.:

>= 188 °C

Pre-test:

Observations	Temperatures
getting pale	Since 30 °C
Started to melt to a milky turbid mass	70 °C
Getting slowly clearer	Since 80 °C
Completely melted to a clear slightly yellow liquid	135 °C
One bubble	144 °C, 168 °C, 176 °C, 181 °C
Individual bubble	Since 185 °C
Lots of fine small bubbles, colour getting darker	Since 200 °C
Bubble chain, gas burner switched off	220 °C
Bubble chain broke	203.6 °C

After cooling down the test item was solidified as a slightly yellow-brown clear solid.Possibly decomposition was considered

Main test:

Observations	Temperatures
	First Determination atmospheric pressure 99760 Pa	Second Determination atmospheric pressure 99734 Pa
Test start: Test item melted immediately to a clear slightly yellow liquid with lots of fine small bubbles, bubbles getting vanish	185.0 °C	185.0 °C
Colourless condensate visible, colour getting darker	Since 188 °C	Since 188 °C
Lots of fine small bubbles	Since 201 °C	Since 197 °C
Boiling chain, gas burner switched off	216.1 °C	213.5 °C
Boiling chain broke	203.6 °C	201.3 °C

No calculation following Sydney-Young was carried out as decomposition (indicated by a colourless condensate and colour change) is considered.

Results:

	Boiling point under decomposition	Pressure in Pa
First determination	203.6 °C (476.8 K)	99760 Pa
Second determination	201.3 °C (474.5 K)	99734 Pa
Mean	202.5°C (475.6 K)

Mean ± standard deviation (without correction following Sydney Young) = 202.5 ± 1.6 °C (475.6 ± 1.6 K).

Conclusions:

The determination of the boiling point of test item was performed following the Siwoloboff Method.
First sign of possibly decomposition indicated by a colourless condensate and colour change were observed since 188°C.
Therefore the boiling point of test item should be stated as: 202.5 ± 1.6 °C (475.6 ± 1.6 K) under decomposition of the test item.
This value is the mean of two independent determinations without Sydney-Young correction.

Executive summary:

The study was performed in order to determine the boiling point of test item according to OECD 103, resp. EU A.2, guideline, using the Siwoloboff method.

The boiling point of test item should be stated as: 202.5 ± 1.6 °C (475.6 ± 1.6 K) under decomposition of the test item.

Description of key information

The boiling point of test item should be stated as: 202.5 ± 1.6 °C (475.6 ± 1.6 K) under decomposition of the test item.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

202.5 °C

Additional information

A fully reliable experimental study, conducted according to OECD 103/ EU A2 guideline is available.

It is considered as a key study, and the result is retained as key data.