Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-334-3 | CAS number: -
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Data waiving:
- other justification
- Justification for data waiving:
- the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
- Justification for type of information:
- In accordance with column 2 of REACH Annex VIII, the acute toxicity by inhalation study (required in section 8.5.2) is appropriate if exposure of humans via inhalation is likely, taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size. Based upon the low vapour pressure of 1.8 x 10-5 Pa the substance is not considered as volatile, also taking into account the boiling point and flash point. Inhalation of the substance is deemed unlikely and it is considered that the substance has low potential to become airborne from the preparations in which the substance is used based on the substances physico-chemical properties. The potential for exposure of humans to aerosols, particles or droplets of an inhalable size is considered unlikely based on the vapour pressure and industrial use patterns of the substance (i.e. adequate measures, such as LEV, are in place to prevent exposure) Therefore, inhalation is not considered to be a significant route of exposure and a study not conducted via this route. In addition, based on the absence of systemic toxicity effects in an acute oral toxicity study and dermal toxicity study, it can be anticipated that an acute inhalation study would not be expected to show evidence of significant systemic toxicity.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
