Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 222-148-7 | CAS number: 3371-33-3
Guidance on Safe Use
Guidance on Safe Use
Administrative data
First-aid measures
- General advice:
Remove from exposure, lie down. Take off immediately all contaminated clothing. Victim to lie down in the recovery position, cover and keep him warm. First Aid responders should pay attention to self-protection and use the recommended protective clothing
- Following inhalation: Move to fresh air. Call a physician immediately.
- Following skin contact: Wash off immediately with plenty of water. Cover wound with sterile dressing. Call a physician immediately.
- Following eye contact: Rinse immediately with plenty of water for at least 15 minutes. Keep eye wide open while rinsing. Call a physician immediately.
- Following ingestion: Rinse mouth. Drink plenty of water. Call a physician immediately.
- Following inhalation: Move to fresh air. Call a physician immediately.
- Following skin contact: Wash off immediately with plenty of water. Cover wound with sterile dressing. Call a physician immediately.
- Following eye contact: Rinse immediately with plenty of water for at least 15 minutes. Keep eye wide open while rinsing. Call a physician immediately.
- Following ingestion: Rinse mouth. Drink plenty of water. Call a physician immediately.
Fire-fighting measures
- Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Water; Foam; Carbon dioxide (CO2); Dry chemical
- Special hazards arising from the substance or mixture: In case of fire and/or explosion do not breathe fumes. Can be released in case of fire: Carbon oxides, Nitrogen oxides (NOx), Hydrogen bromide (HBr)
- Advice for fire fighter: Self-contained breathing apparatus (EN 133) complete suit protecting against chemicals; Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. Collect contaminated fire extinguishing water separately. This must not be discharged into drains. Avoid generating dust; fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
- Special hazards arising from the substance or mixture: In case of fire and/or explosion do not breathe fumes. Can be released in case of fire: Carbon oxides, Nitrogen oxides (NOx), Hydrogen bromide (HBr)
- Advice for fire fighter: Self-contained breathing apparatus (EN 133) complete suit protecting against chemicals; Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. Collect contaminated fire extinguishing water separately. This must not be discharged into drains. Avoid generating dust; fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Accidental release measures
- Personal precautions:
Wear personal protective equipment. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Knock down dust with water spray jet.
- Environmental precautions: Do not flush into surface water or sanitary sewer system.
- Methods and material for containment and cleaning up: Cleaning operations should be carried out only while wearing breathing apparatus. Dust deposits should not be allowed to accumulate on surfaces, as these may form an explosive mixture if they are released into the atmosphere in sufficient concentration. Non-sparking tools should be used. Avoid dispersal of dust in the air (i.e., clearing dust surfaces with compressed air).
Clean-up methods - large spillage: Dampen, pick up mechanically and dispose of.
Clean-up methods - small spillage: Use approved industrial vacuum cleaner for removal.
Keep in suitable, closed containers for disposal.
- Environmental precautions: Do not flush into surface water or sanitary sewer system.
- Methods and material for containment and cleaning up: Cleaning operations should be carried out only while wearing breathing apparatus. Dust deposits should not be allowed to accumulate on surfaces, as these may form an explosive mixture if they are released into the atmosphere in sufficient concentration. Non-sparking tools should be used. Avoid dispersal of dust in the air (i.e., clearing dust surfaces with compressed air).
Clean-up methods - large spillage: Dampen, pick up mechanically and dispose of.
Clean-up methods - small spillage: Use approved industrial vacuum cleaner for removal.
Keep in suitable, closed containers for disposal.
Handling and storage
- Precautions for safe handling:
Advice on safe handling: Provide sufficient air exchange and/or exhaust in work rooms. Routine housekeeping should be instituted to ensure that dusts do not accumulate on surfaces. Minimize dust generation and accumulation. Dry powders can build static electricity charges when subjected to the friction of transfer and mixing operations. Provide adequate precautions, such as electrical grounding and bonding, or inert atmospheres. Breathing must be protected when large quantities are decanted without local exhaust ventilation. Keep container closed when not in use.
Advice on protection against fire and explosion: Keep away from heat and sources of ignition. Take precautionary measures against static discharges. Avoid dust formation.
Hygiene measures: General industrial hygiene practice. Wash hands and face before breaks and immediately after handling the product. Keep working clothes separately.
Dust explosion class: Represents a severe dust explosion hazard.
- Conditions for safe storage, including any incompatibilities:
Requirements for storage areas and containers: Keep tightly closed in a dry and cool place. Keep in a wellventilated place. Protect from heat and direct sunlight. Jointless smooth floor
Advice on common storage: Keep away from food, drink and animal feedingstuffs. Advice on Segregation
Advice on safe handling: Provide sufficient air exchange and/or exhaust in work rooms. Routine housekeeping should be instituted to ensure that dusts do not accumulate on surfaces. Minimize dust generation and accumulation. Dry powders can build static electricity charges when subjected to the friction of transfer and mixing operations. Provide adequate precautions, such as electrical grounding and bonding, or inert atmospheres. Breathing must be protected when large quantities are decanted without local exhaust ventilation. Keep container closed when not in use.
Advice on protection against fire and explosion: Keep away from heat and sources of ignition. Take precautionary measures against static discharges. Avoid dust formation.
Hygiene measures: General industrial hygiene practice. Wash hands and face before breaks and immediately after handling the product. Keep working clothes separately.
Dust explosion class: Represents a severe dust explosion hazard.
- Conditions for safe storage, including any incompatibilities:
Requirements for storage areas and containers: Keep tightly closed in a dry and cool place. Keep in a wellventilated place. Protect from heat and direct sunlight. Jointless smooth floor
Advice on common storage: Keep away from food, drink and animal feedingstuffs. Advice on Segregation
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1-(3,5-dihydroxyphenyl)-2-[[2-(4-hydroxyphenyl)-1- methylethyl]amino]ethan-1-one hydrobromide)
- Labels:
- 9
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1-(3,5-dihydroxyphenyl)-2-[[2-(4-hydroxyphenyl)-1- methylethyl]amino]ethan-1-one hydrobromide)
- Labels:
- 9
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1-(3,5-dihydroxyphenyl)-2-[[2-(4-hydroxyphenyl)-1- methylethyl]amino]ethan-1-one hydrobromide)
- Labels:
- Miscellaneous Dangerous Goods
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
1. Technical protection measures: It is recommended that all dust control equipment such as local exhaust ventilation and material transport systems involved in handling of this product contain explosion relief vents or an explosion suppression system or an oxygen deficient environment. Ensure that dust-handling systems (such as exhaust ducts, dust collectors, vessels, and processing equipment) are designed in a manner to prevent the escape of dust into the work area (i.e., there is no leakage from the equipment). Use only appropriately classified electrical equipment and powered industrial trucks.
2. Hand protection:
Material: Nitrile rubber
Break through time: 480 min
Glove thickness: 0,43 mm
Directive: Protective gloves against chemicals and micro-organisms
Protective index: Class 6
3. Skin and body protection: Laboratory: laboratory coat; factory: disposable Overall.
4. Eye protection: Safety glasses with side-shields
5. Respiratory protection: Respiratory protection not required. Use breathing apparatus if exposed to vapours/dust/aerosol. half mask (EN 140) particle filter P2
6. Protective measures: Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes and clothing. Do not breathe dust. Only use protective equipment in accordance with national/ international regulations. Follow the national regulations about wearing personal protective equipment and the warranty given by the manufacturer for the safe function.
2. Hand protection:
Material: Nitrile rubber
Break through time: 480 min
Glove thickness: 0,43 mm
Directive: Protective gloves against chemicals and micro-organisms
Protective index: Class 6
3. Skin and body protection: Laboratory: laboratory coat; factory: disposable Overall.
4. Eye protection: Safety glasses with side-shields
5. Respiratory protection: Respiratory protection not required. Use breathing apparatus if exposed to vapours/dust/aerosol. half mask (EN 140) particle filter P2
6. Protective measures: Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes and clothing. Do not breathe dust. Only use protective equipment in accordance with national/ international regulations. Follow the national regulations about wearing personal protective equipment and the warranty given by the manufacturer for the safe function.
Stability and reactivity
1. Reactivity
: No dangerous reaction known under conditions of normal use.
2. Chemical stability : No decomposition if stored and applied as directed.
3. Possibility of hazardous reactions : Dust may form explosive mixture in air.
4. Conditions to avoid : No data available
5. Incompatible materials : No data available
6. Hazardous decomposition products: No data available
2. Chemical stability : No decomposition if stored and applied as directed.
3. Possibility of hazardous reactions : Dust may form explosive mixture in air.
4. Conditions to avoid : No data available
5. Incompatible materials : No data available
6. Hazardous decomposition products: No data available
Disposal considerations
- Product: Dispose of in accordance with local regulations.
- Contaminated packaging: Packs that cannot be cleaned should be disposed of in the same manner as the contents. Uncontaminated packaging can be recycled
- Contaminated packaging: Packs that cannot be cleaned should be disposed of in the same manner as the contents. Uncontaminated packaging can be recycled
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
