Registration Dossier

Toxicological information

Eye irritation

Currently viewing:

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Secondary source. Test conditions not in accordance with current test guidelines (test volume; concentration of test material; readings; score; observation period). Documentation insufficient.

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
1999
Report Date:
1999

Materials and methods

Principles of method if other than guideline:
Method: other: no data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals / tissue source

Species:
rabbit

Test system

Vehicle:
not specified
Amount / concentration applied:
Concentration: 5 % active substance
Amount applied: 0.25 ml
Details on study design:
Comment: not rinsed

Results and discussion

Any other information on results incl. tables

Irritation symptoms included necrosis of the cornea.

Applicant's summary and conclusion

Conclusions:
Invalid study.