Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary source

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1978
Report date:
1978
Reference Type:
publication
Title:
Unnamed
Year:
1982
Report date:
1982

Materials and methods

Principles of method if other than guideline:
Method: no data provided
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methylvaleric acid
EC Number:
202-594-9
EC Name:
2-methylvaleric acid
Cas Number:
97-61-0
Molecular formula:
C6H12O2
IUPAC Name:
2-methylpentanoic acid

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Details on study design:
no data
Statistics:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 500 mg/kg bw
95% CL:
1 300 - 4 810

Applicant's summary and conclusion

Conclusions:
A secondary source reported a dermal LD50(rabbit) of 2500 (1300-4810) mg/kg bw but no methodological details.