Resinoid of Canarium luzonicum (Burseraceae) obtained from the exudate by benzyl benzoate extraction

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

6 December 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The study was conducted according to an internationally recognised method. Test substance is adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

2009

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

Inspected on 13 and 14 October 2014 / Signed on 8 April 2015

Type of method:

static method

Key result

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

791 Pa

Key result

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

1 007 Pa

The measured values are presented in the following table:

1. Determination increasing temperature			2. Determination decreasing temperature
Temp. in °C	Time	Pressure in hPa	Temp. in °C	Time	Pressure in hPa
20.0	08:30	8.5	48.1	11:03	27.7
28.9	09:00	11.8	39.1	11:35	20.5
38.1	09:30	18.5	30.0	12:20	13.4
47.1	10:00	27.3	21.0	13:40	8.9
56.1	10:24	35.0	15.9	14:50	5.4

The parameters for the linear regression of the graph log (p) vs. 1/T are presented in the following table:

Parameter	Value
Slope	-1833.939236
Intercept	9.153934839
Correlation coefficient r	-0.991050727
Coefficient of determination r^2	0.982181544

Using the equation vapour pressures at ambient temperature were calculated as:

Parameter	Value	Unit
Vapour Pressure (20 °C)	791	Pa
Vapour Pressure (25 °C)	1007	Pa

Conclusions:

Using the static method, vapour pressures of 791 Pa at 20 °C and 1007 Pa at 25 °C were determined.
These values were calculated from the regression of 10 individual measurements, which were performed in a temperature range of 15.9 – 56.1 °C.
The measured values for pressure p and temperature T were used to calculate pairs of log p and 1/T. These values were plotted, from the linear regression, vapour pressures at ambient temperature were determined.

Executive summary:

The study was performed in order to determine the vapour pressure of test item according to OCED 104, resp. EU A.4 guideline, using the static method.

The vapour pressure of test item was determined to be 791 Pa at 20°C and 1007 Pa at 25°C.

Description of key information

The vapour pressure of test item was determined to be 791 Pa at 20°C and 1007 Pa at 25°C.

These values were calculated from the regression of10individual measurements, which were performed in a temperature range of 15.9 – 56.1 °C.

Key value for chemical safety assessment

Vapour pressure:

791 Pa

at the temperature of:

20 °C

Additional information

A fully reliable experimental study, conducted according to OECD 104 /EU A4 guideline, using static method, is available. It is considered as a key study, and the result is retained as key data.