Registration Dossier

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
publication
Title:
Risk assessment in immunotoxicology: Sensitivity and predictability of immune tests
Author:
Luster, M.I., Portier, C., Pait, D.G., White, K.L., Gennings, C., Munson, A.E., Rosenthal, G.J.
Year:
1992
Bibliographic source:
Fundamental Applied Toxicology Vol 18, pp 200-210

Materials and methods

Type of study / information:
Type: other: Hypersensitization
Principles of method if other than guideline:
No method cited

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
TS-Freetext:
Tetraethyl lead (TEL).

Results and discussion

Applicant's summary and conclusion

Conclusions:
When TEL was administered in three different concentrations to test animals, over 14 days via stomach tube, hypersensitization and a raised leucocyte count were detected
Executive summary:

When TEL was administered in three different concentrations to test animals, over 14 days via stomach tube, hypersensitization and a raised leucocyte count were detected