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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-12-19 to 2017-12-22
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Version / remarks:
2004
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Version / remarks:
2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis[N-(2-hydroxyethyl)-N-methylglycinato-N,O,ON]copper
EC Number:
300-491-4
EC Name:
Bis[N-(2-hydroxyethyl)-N-methylglycinato-N,O,ON]copper
Cas Number:
93940-93-3
Molecular formula:
C10H20CuN2O6
IUPAC Name:
bis[N-(2-hydroxyethyl)-N-methylglycinato-N,O,ON]copper
Test material form:
solid: particulate/powder

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
< -2
Temp.:
20.8 °C
pH:
>= 8.13 - <= 8.17
Remarks on result:
other: below determination limit of the method
Details on results:
The determined values of the logarithms of the partition coefficients were within the acceptable range of ± 0.3 log units for each pH value.

Applicant's summary and conclusion

Conclusions:
The determined partition coefficient of test item at 20.8 ± 1 °C is log Pow <-2.
Executive summary:

The n-octanol/water partition coefficient of the test item was determined according to OECD guideline 107 and EC method A.8 (440/2008/EEC). For the determination of the n‑octanol/water partition coefficient of the test item the shake-flask method was used. The main test was performed in water at three different ratios of n-octanol and water (1/1, 2/1 and 1/2).

The concentration of the test item in the water phase and in the n‑octanol phase was taken for the calculation of n‑octanol/water partition coefficient (Pow) and its decimal logarithm (log Pow). The determined partition coefficient log POW at 20.8 ± 1 °C is < -2 (below determination limit of the method).

The pH values of the water phases after shaking were determined to be between 8.13 and 8.17.