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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1974
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1974
Report date:
1974

Materials and methods

Principles of method if other than guideline:
Even if the guideline followed is not indicated, based on the available study details, the method is considered as comparable to the OECD Guideline 401 (1981).
GLP compliance:
no
Remarks:
test performed before GLP compliance
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction products of diazotised 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid, coupled with 1,3-diaminobenzene and diazotised sodium 4-aminobenzenesulfonate, metallised with Basic Chromium (III) Sulphate
EC Number:
947-395-4
Molecular formula:
not applicable
IUPAC Name:
Reaction products of diazotised 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid, coupled with 1,3-diaminobenzene and diazotised sodium 4-aminobenzenesulfonate, metallised with Basic Chromium (III) Sulphate
Test material form:
solid: particulate/powder

Test animals

Species:
rat
Strain:
not specified
Sex:
male

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
DMSO
Details on oral exposure:
VEHICLE
- Amount of vehicle: 1.0 ml / 100 g of body weight
Doses:
5000 mg/kg
No. of animals per sex per dose:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
other: not classified according to the CLP Regulation (EC 1272/2008)
Conclusions:
The LD50 (oral, rat) was found to be greater than 5000 mg/kg bw.
Executive summary:

The substance was administered by gavage to a group of male rats at a dose level of 5000 mg/kg.

The LD50 (rat, oral) was found to be greater than 5000 mg/kg bw.

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