Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1995
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
The volume of Hansch and Leo contains 16 777 measured octanol-water log P values. This publication is well known and considered as reliable although it is difficult to recover the original source publication (then reliability is set to klimish 2 score).

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Exploring QSAR - Hydrophobic, Electronic, and Steric Constants.
Author:
C. Hansch, A. Leo, and D. Hoekman.
Year:
1995
Bibliographic source:
Washington, DC: American Chemical Society
Report Date:
1996
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Experimental data from a widely used and accepted publication
Type of method:
other: not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Specific details on test material used for the study:
detail not specified

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
ca. -2.29
Temp.:
25 °C
pH:
ca. 7
Remarks on result:
other:
Remarks:
pH and Temp not specified, by default

Applicant's summary and conclusion

Conclusions:
erythritol Log Kow is -2.29
Executive summary:

According to Hansch et al. (1995), erythritol Log Kow is -2.29