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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Version / remarks:
In addition, the procedures were designed to meet the test methods of the following guidelines and guidance document:
• Commission Regulation (EC) No 440/2008 of 30 May 2008, Part C: Methods for the determination of ecotoxicity, Publication No. L142, C.2. "Daphnia Sp. Acute Immobilisation Test".
• ISO International Standard 6341: "Water quality - Determination of the inhibition of the mobility of Daphnia magna Straus - Acute toxicity test, Third edition, 1996-04-01.
• Guidance document on aquatic toxicity testing of difficult substances and mixtures, OECD series on testing and assessment number 23, December 14, 2000.
Deviations:
no
GLP compliance:
yes
Remarks:
Not certificate

Test material

Constituent 1
Test material form:
solid: particulate/powder

Test organisms

Test organisms (species):
Daphnia magna

Study design

Total exposure duration:
48 h

Results and discussion

Effect concentrations
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.47 mg/L
Conc. based on:
test mat. (dissolved fraction)
Remarks on result:
not determinable
Remarks:
Under the conditions of the present study 1574 CETONA did not induce acute immobilisation of Daphnia magna at 0.47 mg/l after 48 hours of exposure. The 48h-EC50 was beyond the range tested, i.e. exceeded an initially measured concentration of 0.47 mg/l. This concentration was considered the maximum soluble concentration in the test medium. Due to the low solubility of 1574 CETONA in test medium, concentrations toxic to daphnids could not be reached.

Applicant's summary and conclusion

Conclusions:
Under the conditions of the present study 1574 CETONA did not induce acute immobilisation of Daphnia magna at 0.47 mg/l after 48 hours of exposure.
The 48h-EC50 was beyond the range tested, i.e. exceeded an initially measured concentration of 0.47 mg/l. This concentration was considered the maximum soluble concentration in the test medium.
Due to the low solubility of 1574 CETONA in test medium, concentrations toxic to daphnids could not be reached.