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EC number: 923-900-3 | CAS number: -
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
After a 21d-exposure period under semi static conditions no toxic effects on reproduction and mortality against Daphnia were observed up to three-fold of the water solubility (NOEL > 10 mg/l).
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater invertebrates:
- 10 mg/L
Additional information
"Should read: NOEL > 10 mg/L"
A study was performed to assess the effects of the substance on the reproductive output of parthenogenetic Daphnia magna STRAUS under semi static conditions. The study was conducted in accordance with Council Regulation (EC) No 440/2008, Method C.20 'Daphnia magna Reproduction Test'' (2008), which equals in all relevant parts to the OECD Test guideline 211 (Daphnia magna Reproduction Test; adopted: Oct. 03, 2008). Young female Daphnia, aged less than 24 hours at the start of the test, were exposed to two concentrations, nominally 3 and 10 mg/L of the test item dissolved in water. Auxiliaries used to prepare the test media were on a magnetic stirrer and an aseptic filter. After a 21d-exposure period, the total number of living offspring produced per parent animal alive at the end of the test was assessed. The reproductive output of the Daphnia exposed to the test item was compared to that of the control in order to determine the Lowest Observed Effect Loading (LOEL) and the No Observed Effect Loading (NOEL) according to Williams / Dunnett's Multiple Sequential t-Test Procedure. Additionally, the survival of the parent Daphnia and the time to production of first brood was determined.
No toxic effects on reproduction and mortality against Daphnia were observed up to three-fold of the water solubility under exposure conditions. The test item is insoluble or only poorly soluble in water. A suitable selective and sensitive chromatographical method for the determination of the test item in aqueous solutions could not be established. Therefore an accompanying analysis by the means of a chromatographical method cannot be performed. The quantification of the test item was performed by DOC determination.
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