Sodium O,O-diisopropyl dithiophosphate

Toxicity to microorganisms

Administrative data

Endpoint:

activated sludge respiration inhibition testing

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2012-08-16 - 2012-09-13

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2012

Report date:

2012

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: OECD Guideline 301 D (Ready Biodegradabality: Closed Bottle Test)

Deviations:

no

Principles of method if other than guideline:

In biodegradation test OECD 301 D the oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Sodium O,O-diisobutyl dithiophosphate

EC Number:

258-508-5

EC Name:

Sodium O,O-diisobutyl dithiophosphate

Cas Number:

53378-51-1

Molecular formula:

C8H18NaO2PS2

IUPAC Name:

Sodium O,O-diisobutyl phosphorodithioate

Test organisms

Test organisms (species):

sewage, domestic

Details on inoculum:

Secondary effluent from a municipal wastewater treatment plant in Usserød, Denmark, wihich predominantly receives domestic sewage

Study design

Total exposure duration:

28 d

Test conditions

Reference substance (positive control):

yes

Remarks:

benzoic acid, sodium salt

Results and discussion

Effect concentrations

Key result

Duration:

28 d

Dose descriptor:

other: oxygen consumption

Effect conc.:

30.6 other: % of ThOD

Nominal / measured:

meas. (not specified)

Conc. based on:

other: oxygen elektrode

Basis for effect:

inhibition of total respiration

Remarks:

respiration rate

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

In biodegradation test OECD 301 D the oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline
Remark: The test solution contains NaOH due to the production method.