Registration Dossier
Registration Dossier
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EC number: 248-322-2 | CAS number: 27205-99-8
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-08-16 - 2012-09-13
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 D (Ready Biodegradabality: Closed Bottle Test)
- Deviations:
- no
- Principles of method if other than guideline:
- In biodegradation test OECD 301 D the oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Sodium O,O-diisobutyl dithiophosphate
- EC Number:
- 258-508-5
- EC Name:
- Sodium O,O-diisobutyl dithiophosphate
- Cas Number:
- 53378-51-1
- Molecular formula:
- C8H18NaO2PS2
- IUPAC Name:
- Sodium O,O-diisobutyl phosphorodithioate
Constituent 1
Test organisms
- Test organisms (species):
- sewage, domestic
- Details on inoculum:
- Secondary effluent from a municipal wastewater treatment plant in Usserød, Denmark, wihich predominantly receives domestic sewage
Study design
- Total exposure duration:
- 28 d
Test conditions
- Reference substance (positive control):
- yes
- Remarks:
- benzoic acid, sodium salt
Results and discussion
Effect concentrations
- Key result
- Duration:
- 28 d
- Dose descriptor:
- other: oxygen consumption
- Effect conc.:
- 30.6 other: % of ThOD
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: oxygen elektrode
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- In biodegradation test OECD 301 D the oxygen consumption corresponded to 30.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline
Remark: The test solution contains NaOH due to the production method.
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