Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Title:
Range-Finding Toxicity Data: List VII
Author:
Henry F. Smyth Jr. Ph.D. , Charles P. Carpenter Ph.D. , Carrol S. Weil , Urbano C. Pozzani , Jean A. Striegel & Judith S. Nycum
Year:
1969
Bibliographic source:
American Industrial Hygiene Association Journal, Vol. 30, Pg. 470-476

Materials and methods

GLP compliance:
not specified

Test material

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
No details

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
No details
Doses:
No details
No. of animals per sex per dose:
No details
Control animals:
not specified
Details on study design:
No details
Statistics:
No details

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 160 mg/kg bw
Based on:
test mat.
Mortality:
No details
Clinical signs:
No details
Body weight:
No details
Gross pathology:
No details
Other findings:
No details

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
The article review cites a rat oral LD50 value of 160 mg/kg body weight. No further details are available.
Executive summary:

The article review cites a rat oral LD50 value of 160 mg/kg body weight. No further details are available.