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EC number: 812-526-5 | CAS number: 53831-80-4
m-Aminophenol induced contact sensitisation in a murine Local Lymph Node Assay and was
rated to have a strong sensitisation potential.
A Local Lymph Node Assay was conducted in female CBA/J mice to investigate the sensitisation potential of m-aminophenol. Concentrations up to 25% (the maximum soluble concentration) in dimethylformamide were tested in two successive experiments. A positive control group received 25% alpha-hexylcinnamaldehyde in dimethylformamide. No mortality, clinical signs or body weight changes could be attributed to compound administration. An increase in stimulation index was observed with increasing dose and the threshold positive value of 3 was exceeded at concentrations of 0.5% and higher.
m-Aminophenol induced contact sensitisation in a murine Local Lymph Node Assay and was rated to have a strong sensitisation potential.
Classified as Category 1 for skin sensitisation potential according to EC 1272/2008.
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