Registration Dossier
Registration Dossier
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EC number: 200-720-7 | CAS number: 69-93-2
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- QSAR
- Justification for type of information:
- QSAR
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- QSAR
- GLP compliance:
- no
Test material
- Reference substance name:
- Uric acid
- EC Number:
- 200-720-7
- EC Name:
- Uric acid
- Cas Number:
- 69-93-2
- Molecular formula:
- C5H4N4O3
- IUPAC Name:
- 7,9-dihydro-1H-purine-2,6,8(3H)-trione
- Test material form:
- solid: particulate/powder
- Details on test material:
- It was manufactured by MOLAR CHEMICALS Ltd.
1
Results and discussion
Test results
- Key result
- Remarks on result:
- no mutagenic potential (based on QSAR/QSPR prediction)
- Remarks:
- QSAR
Applicant's summary and conclusion
- Conclusions:
- The bacterial in vitro mutagenicity QSAR predicttion result is negative.
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