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Density

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Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04 October 2017 - 19 October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method. Test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
2008
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. QA statement)
Remarks:
Inspected on 13 and 14 October 2014/ Signed on 8 April 2015
Type of method:
pycnometer method
Key result
Type:
relative density
Density:
1.071 other: no dimension
Temp.:
20 °C

All measured values are given in the following table:

First Determination

 

 

 

 

 

Weighing #

m1

m2

m3

m4

m5

Item

Pycn. empty

Pycn.+ H2O

Pycn. + repl.liq.

Pycn. + test item

Pycn. + test item + repl. liq.

Mass in g

36.7398

61.6009

61.6021

40.0576

61.8458

Temperature in °C

20.4

20.4

20.2

19.8

20.2

Second Determination

 

 

 

 

 

Weighing #

m1

m2

m3

m4

m5

Item

Pycn. empty

Pycn.+ H2O

Pycn. + repl.liq.

Pycn. + test item

Pycn. + test item + repl. liq.

Mass in g

36.7408

61.6015

61.6077

40.0591

61.8173

Temperature in °C

20.4

20.2

20.4

20.4

20.4

The following values were calculated:

First Determination

 

 

Error rel.

Error abs.

Temperature

20.4

 °C

 

0.1

Density of water

0.998098

g/cm3

2.00%

0.0002

Volume of Pycnometer

24.9085

cm3

 

 

Density of Replacement Liquid

0.9981

g/cm3

 

 

Density of Test Item

1.0773

g/cm3

0.0619%

0.0007

Second Determination

 

 

Error rel.

Error abs.

Temperature

20.2

 °C

 

0.1

Density of water

0.998203

g/cm3

2.00%

0.0002

Volume of Pycnometer

24.9055

cm3

 

 

Density of Replacement Liquid

0.9985

g/cm3

 

 

Density of Test Item

1.0658

g/cm3

0.0615%

0.0007

The mean value is presented in the following table:

Parameter

Value

Unit

Standard Deviation

Relative Standard Deviation

Volume of Pycnometer

24.91

cm3

0.0021

0.01%

Density of Test Item

1.0715

g/cm3

0.0081

0.76%

Density of Test Item

1071.5

kg/m3

8.1

0.76%

Relative Density of Test Item

1.0715

 

0.0081

0.76%

Conclusions:
Using the pycnometer method, a density of 1.0715 ± 0.0007 g/cm3 at 20.0 ± 0.4°C was measured.
This value is the mean of two independent determinations with the maximum error of a single determination.
Standard deviation was 0.0081 g/cm3, showing acceptable correlation of the two determinations.
Executive summary:

The study was performed in order to determine the density of test item according to OECD 109, resp. EU A.3 guideline, using a pycnometer.

A density of 1.0715 ± 0.0007 g/cm3 at 20.0 ± 0.4°C was measured.

This value is the mean of two independent determinations with the maximum error of a single determination.

Standard deviation was 0.0081 g/cm3, showing acceptable correlation of the two determinations.

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13 November 2017- 11 January 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method. Test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
2008
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. QA statement)
Remarks:
Inspected on 13 and 14 October 2014/ Signed on 8 April 2015
Type of method:
pycnometer method
Key result
Type:
relative density
Density:
1.046 other: no dimension
Temp.:
20 °C

All measured values are given in the following table:

First Determination

 

 

 

 

 

Weighing #

m1

m2

m3

m4

m5

Item

Pycn. empty

Pycn.+ H2O

Pycn. + repl.liq.

Pycn. + test item

Pycn. + test item + repl. liq.

Mass in g

38.0038

88.3416

88.3489

47.8469

88.8155

Temperature in °C

19.8

19.8

20.2

20.0

19.6

Second Determination

 

 

 

 

 

Weighing #

m1

m2

m3

m4

m5

Item

Pycn. empty

Pycn.+ H2O

Pycn. + repl.liq.

Pycn. + test item

Pycn. + test item + repl. liq.

Mass in g

38.0036

88.3374

88.3616

46.6250

88.7431

Temperature in °C

19.6

20.0

20.0

20.0

20.2

The following values were calculated:

First Determination

 

 

Error rel.

Error abs.

Temperature

19.8

 °C

 

0.1

Density of water

0.998203

g/cm3

2.00%

0.0002

Volume of Pycnometer

50.4284

cm3

 

 

Density of Replacement Liquid

0.9983

g/cm3

 

 

Density of Test Item

1.0480

g/cm3

0.0213%

0.0002

Second Determination

 

 

Error rel.

Error abs.

Temperature

20.0

 °C

 

0.1

Density of water

0.998203

g/cm3

2.00%

0.0002

Volume of Pycnometer

50.4244

cm3

 

 

Density of Replacement Liquid

0.9987

g/cm3

 

 

Density of Test Item

1.0449

g/cm3

0.0239%

0.0002

Results of the single determinations with the respective error as well as the mean value and its standard deviation are presented in the following tables:

Determination

Density in g/cm3

Error of Determ. in g/cm3

1

1.0480

0.0002

2

1.0449

0.0002

Parameter

Value

Unit

Standard Deviation

Relative Standard Deviation

Volume of Pycnometer

50.43

cm3

0.0028

0.01 %

Density of Test Item

1.0465

g/cm3

0.0022

0.21 %

Density of Test Item

1046.5

kg/m3

2.2

0.21 %

Relative Density of Test Item

1.0465

-

0.0022

0.21 %

Conclusions:
Using the pycnometer method, a density of 1.0465 ± 0.0002 g/cm3 at 20 ± 0.4 °C was measured. This value is the mean of two independent determinations with the maximum error of a single determination.
Standard deviation was 0.0022 g/cm3, showing good correlation of the two determinations.
Executive summary:

The study was performed in order to determine the density of test item according to OECD 109, resp. EU A.3 guideline, using a pycnometer.

The density of test item was determined to be 1.0465 g/cm3 at 20°C (relative density 1.0465).

Description of key information

The density was determined to be between 1.0465 and 1.0715 g/cm3.

Key value for chemical safety assessment

Additional information

Two fully reliable experimental studies, conducted according to OECD 109 /EU A3 guideline, using pycnometer, are available.

Both are considered as a key study, and the result is retained as key data.