Registration Dossier

Diss Factsheets

Administrative data

Link to relevant study record(s)

basic toxicokinetics in vitro / ex vivo
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:

Description of key information

No specific toxicokinetic data is available on Toluene-4-sulphonohydrazide (TSH). Data from a recently performed OECD 422 oral study showed that the substance was absorbed as severe systemic effects was seen. But, as no specific data for the absorption rate from the oral, the dermal or the inhalational route of exposure is available, default assumption will be applied. Thus, absorption from dermal and inhalational route is considered to be the same as for the oral route.

Key value for chemical safety assessment

Absorption rate - oral (%):
Absorption rate - dermal (%):
Absorption rate - inhalation (%):

Additional information