Registration Dossier
Registration Dossier
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EC number: 258-081-5 | CAS number: 52663-87-3
Endpoint summary
Administrative data
Description of key information
Biodegradation: The test material attained 91% degradation after 28 days.
Bioaccumulation: Bioconcentration factor (BCF) for the registered substance is predicted to be 3.162 L/kg wet weight (BCFBAF v3.01).
Adsorption coefficient: Log Koc for the substance is predicted to lie in the range -0.363 to 3.059 (EpiSuite KOCWIN v2.00).
Additional information
Biodegradation
The test material at a concentration of 10 mg C/L was exposed to activated sewage sludge microorganisms with culture medium in sealed culture vessels in the dark at 21 °C for 28 days. Control solutions with inoculum and the standard material, sodium benzoate, were used for validation purposes together with a toxicity control. The test material attained 91% degradation after 28 days. By inspection of the degradation curve, the test material achieved 10 % degradation between days 4 and 5 and 60 % degradation between days 13 and 14 thereby satisfying the 10 -day window validation criterion whereby 60 % degradation must be attained within 10 days of the degradation rate exceeding 10 %. The test material can therefore be considered to be readily biodegradable under the strict terms and conditions of OECD Guideline 301 B.
Bioaccumulation
Bioconcentration factor (BCF) for the registered substance is predicted to be 3.162 L/kg wet weight and, in accordance with ECHA guidance on Information Requirements and Chemical Safety Assessment Chapter R.11: PBT/vPvB assessment (Version 3.0; June 2017), bioaccumulation is not expected when the aquatic BCF of a substance is < 2000 L/kg.
Adsorption coefficient
Affinity of the substance to soil is predicted to be low to medium because Log Koc is expected to lie in the range < 1 to 4.
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