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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

Because all enzymes are built up of the combination of the same 20 common amino acids, the physical and chemical characteristics are very similar for different enzymes, and hence, read-across from other enzymes should be fully applicable. The logPow value of the present target substance has not been determined but other enzymes have been analysed and the LogPow from literature studies was found to be between -3.1 to -2.95.

In addition, the octanol-water partition coefficient (logPow) for glucoamylase was measured <= -1.3 at 20°C.

Due to the similar nature of enzymes, this value can also be extrapolated to other enzymes.


- Basketter D, Berg N, Broekhuizen C, Fieldsend M, Kirkwood S, Kluin C, Mathieu S, Rodriguez C (2012a). Enzymes in Cleaning Products: An Overview of Toxicological Properties and Risk Assessment/Management. Regul. Toxicol. Pharmacol., 64(1):117-123.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information