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Diss Factsheets
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EC number: 229-158-0 | CAS number: 6420-33-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 October 2016 to 02 December 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 835.3110 (Ready Biodegradability)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: from the aeration stage of the Severn Trent Water Plc sewage treatment plant at Loughborough, Leicestershire, UK
- Storage conditions: washed sample is maintained in mineral medium (acc yo OECD 310) on continuous aeration at approximately 21 ºC
- Storage length:< 1 day
- Preparation of inoculum for exposure: in oculum at concentration of 30 mg SS/L
- Duration of test (contact time):
- 29 d
- Initial conc.:
- 10 other: mgC/L
- Based on:
- act. ingr.
- Initial conc.:
- 22.9 mg/L
- Based on:
- act. ingr.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD301
- Test temperature: 22-24 °C,
- pH: pre-treatment 7.7; after adjustment 7.5-7.6; on day 28 7.5-7.7
- Aeration of dilution water: CO2-free air
- Suspended solids concentration: 30 mgSS/L
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: 5 liter vessels
- Number of culture flasks/concentration: 2 vessels for controls, reference and test item, toxicity controls 1 velssel
- Method used to create aerobic conditions: bubbling of vessels with CO2-free air
- Test performed in open system: yes
- Details of trap for CO2 and volatile organics if used: NaOH in Dreschel bottle (2 traps)
SAMPLING
- Sampling frequency: first absorber on day 0, 2, 6, 8, 10, 14, 21, 28 and 29; second absorber on day 0 and 29
- Sample storage before analysis: either analysed directly or stored frozen
CONTROL AND BLANK SYSTEM
- Inoculum blank: in duplicate
- Abiotic sterile control: NA
- Toxicity control: single veseel
- Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- No indication of adsorption (filtered solutions 84-93% of nominal C-content)
- Test performance:
- positive control and toxicity control showed sufficient degradation to pass the validity criteria
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 21 d
- Remarks on result:
- other:
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 1
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 9
- Sampling time:
- 29 d
- Remarks on result:
- other: after acidification with HCl
- Results with reference substance:
- the reference study attained 78% degradation over 14 days and 77% degradation at the end of the study
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The substance is not readily biodegradable
- Executive summary:
In a CO2 evolution test the substance sludge was exposed to the substance over a 29 day period. No CO2 evolution was reported. Therefore the substance is considered not readily biodegradable.
Reference
Day |
% Biodegradation
|
||
|
Procedure Control |
Test Item |
Toxicity Control |
0 |
0 |
0 |
0 |
2 |
57 |
0 |
31 |
6 |
59 |
0 |
38 |
8 |
71 |
0 |
35 |
10 |
71 |
0 |
34 |
14 |
78 |
0 |
37 |
21 |
79 |
0 |
35 |
28 |
83 |
1 |
37 |
29 |
77 |
9 |
53 |
Description of key information
In a CO2 evolution test sludge was exposed to the substance over a 29 day period. No CO2 evolution was reported. Maximum degradation 9%. Therefore the substance is considered not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.