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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 July 2008 to 17 November 2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted to GLP in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.
Reference:
Composition 0
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry
Test material information:
Composition 1
Boiling pt.:
541 K
Atm. press.:
100.89 kPa
Decomposition:
yes
Remarks on result:
other: Determination 1 (performed under air, static)
Boiling pt.:
536 K
Atm. press.:
100.89 kPa
Decomposition:
yes
Remarks on result:
other: Determination 2 (performed under nitrogen)

Table 1: Thermographic Data

 

Thermal Event

Interpretation

Temperature

 

°C

K

Determination 1 (0.0051 g)

Broad endotherm

Start of decomposition

268

541

Determination 2 (0.0051 g)

Broad endotherm

Start of decomposition

263

536

Conclusions:
Under the conditions of the study, the boiling point of the test material was determined (mean of 2 determinations) as overall decompostion temperature onset, (approximately) 536 to 541 K.
Executive summary:

The boiling point of the test material was investigated in study; conducted under GLP conditions and in accordance with the standardised guideline EU Method A.2., by differential scanning calorimetry.

As a result of the low rate of enthalpy change during decomposition, the onset temperature could only be approximated. Similar thermographic profiles were obtained using air and nitrogen atmospheres; this indicated that the observed decomposition in both determinations was probably thermal and not oxidative.

The test material has been determined to decompose from approximately 536 K at 100.89 kPa. As the test material decomposed, no value for boiling temperature could be determined.

A calculated value of boiling temperature gave a result of 612 K at 101.325 kPa.

Under the conditions of the study, the boiling point of the test material was determined (mean of 2 determinations) as overall decompostion temperature onset, (approximately) 536 to 541 K.

Description of key information

Boiling point (with decomposition) = 536 K, EU Method A.2., differential scanning calorimetry, Butler & O'Connor (2008)

A calculated value of boiling temperature gave a result of 612 K at 101.325 kPa.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
612 K

Additional information

The boiling point of the test material was investigated in study; conducted under GLP conditions and in accordance with the standardised guideline EU Method A.2., by differential scanning calorimetry. The study was assigned a reliability score of 1 in line with the principles for assessing data quality as defined by Klimisch (1997).

As a result of the low rate of enthalpy change during decomposition, the onset temperature could only be approximated. Similar thermographic profiles were obtained using air and nitrogen atmospheres; this indicated that the observed decomposition in both determinations was probably thermal and not oxidative.

The test material has been determined to decompose from approximately 536 K at 100.89 kPa. As the test material decomposed, no value for boiling temperature could be determined.

A calculated value of boiling temperature gave a result of 612 K at 101.325 kPa.

Under the conditions of the study, the boiling point of the test material was determined (mean of 2 determinations) as overall decompostion temperature onset, (approximately) 536 to 541 K.