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EC number: 947-279-3 | CAS number: -
Cedrene washed when applied at the concentrations of 30% and 10% in ethanol, induced slight to severe cutaneous responses accompanied by dry scaling during the induction phase of the study. The test article, however, did not induce any skin reactions as such in the test or contorl animals during the challenge phase of the experiment when applied at the concentrations 3% or lower.
Based on the above experimental data, it is concluded that the topically applied Cedrene washed when used under the conditions of this study (<3%) did not induce skin sensitization in the guinea pig. Considering the predictive value of the guinea pig skin sensitization test it can be assumed that cutaneous exposure to Cedrene washed at the concentrations of equal to or lower than 3% in ethanol is unlikely to give rise to skin sensitization in man.
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