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EC number: 807-365-2 | CAS number: 127961-54-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 - 17 Jun 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 850.1010 (Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Sucrose tetrastearate triacetate
- IUPAC Name:
- Sucrose tetrastearate triacetate
1
Sampling and analysis
- Analytical monitoring:
- no
- Remarks:
- Due to the complexity of the product, there is no suitable method for measuring the test solution concentrations.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: The test substance was weighed in a tared glass beaker for each concentration. The substance was then rinsed with dilution water into glass aspirator bottles to a final volume of 3 L. The test solutions were mixed for about 48 hrs. After the mixing, the solutions were allowed to settle for 4 hrs, and then decanted into test chambers from spigot and tubing placed 2-3 cm from the bottom.
- Controls: A negative control was prepared using only dilution water. The negative control solution was clear throughout the test with no evidence of precipitate.
- Evidence of undissolved material (e.g. precipitate, surface film, etc.): Yes, all test solutions had a white color and precipitate when first made. By the end of the test, the 63-500 mg/L test solutions were colorless, but showed white precipitate at the bottom of the test vessels. The 1000 mg/L solution was still slightly white in color with white precipitate at the bottom and in the water column.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Source: Wildlife International of Easton, Maryland, USA
- Age of parental stock (mean and range, SD): At least 28 days, and had produced at least one previous brood.
- Feeding during test: no
METHOD FOR PREPARATION AND COLLECTION OF EARLY INSTARS OR OTHER LIFE STAGES: Neonates < 24 hrs old were used in the test.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 144-148 mg/L CaCO3
- Test temperature:
- 19.8 - 20.6 °C
- pH:
- 8.1 - 8.4
- Dissolved oxygen:
- ≥ 91%
- Conductivity:
- 329-359 µS/cm
- Nominal and measured concentrations:
- Nominal: 0, 63, 125, 500, 1000 mg/L
Measured: Concentrations were not measured due to the lack of a suitable analytical method. - Details on test conditions:
- TEST SYSTEM
- Test vessel: 250 mL glass beakers
- Material, size, headspace, fill volume: glass, 250 mL, filled with 220 mL test solution
- Aeration: No
- Type of flow-through (e.g. peristaltic or proportional diluter): static test
- Renewal rate of test solution (frequency/flow rate): not renewed
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: well water, 40 m deep
- Total organic carbon: < 1 mg C/L
- Metals: Below limit of detection.
- Pesticides: Below limit of detection.
- Chlorine: 4.3 mg/L
- Alkalinity: 176-178 mg/L CaCO3
- Ca/mg ratio: 34.9/13.4 mg
- Conductivity: 329-359 uS/cm
- Culture medium different from test medium: No
- Intervals of water quality measurement: Within 4-weeks of test.
OTHER TEST CONDITIONS
- Photoperiod: 16 hrs light/8 hrs dark with 30 min transition period.
- Light intensity: 591 lux
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): Observations for immobility, abnormal behavior, and signs of toxicity were made at 3, 24, and 48 hrs after start of exposure. - Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOELR
- Effect conc.:
- >= 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- - Behavioural abnormalities: One daphnid in the 125 mg/L group was lethargic at the 24 hr observation. As this daphnid recovered, and no other daphnids at this or the 500 mg/L concentration showed lethargy, this was considered incidental. Two daphnids in the 1000 mg/L concentration group were lethargic at the 24 hr observation, but not at the 48 hr observation.
- Mortality of control: None
- Any observations (e.g. precipitation) that might cause a difference between measured and nominal values: White color of the test solutions and precipitate was noted at all test concentrations.
- Effect concentrations exceeding solubility of substance in test medium: yes - Reported statistics and error estimates:
- Since no effects were visible in this study statistical analysis were not necessary.
Any other information on results incl. tables
Concentration | Number Immobile 3 hr Observation |
Number Immobile 24 hr Observation |
Number Immobile 48 hr Observation |
Control | 0 | 0 | 0 |
63 mg/L | 0 | 0 | 0 |
125 mg/L | 0 | 0 | 0 |
500 mg/L | 0 | 0 | 0 |
1000 mg/L | 0 | 0 | 0 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 48-hr EL50 for daphnids is > 1000 mg/L (WAF).
- Executive summary:
The acute toxicity of the test substance to Daphnia magna was determined in an OECD Guideline 202 study. Daphnids were exposed to loading rates of 0, 63, 125, 500, 1000 mg/L (water accommodated fraction) of test substance. At the 24 hr observation, some daphnids showed lethargy, but all had recovered by the 48 hr observation. The EL50 (48 h) for the test substance is >1000 mg/L (WAF).
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