Registration Dossier
Registration Dossier
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EC number: 604-013-8 | CAS number: 13732-69-9
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Data source
Reference
- Reference Type:
- other: prediction
- Title:
- QSAR prediction of levonorgestrel acetate
- Author:
- Gedeon Richter Plc.
- Year:
- 2 016
- Bibliographic source:
- QSAR Toolbox
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- QSAR
Test material
- Reference substance name:
- (17β)-13-Ethyl-17-ethynyl-3-oxogon-4-en-17-yl acetate
- EC Number:
- 604-013-8
- Cas Number:
- 13732-69-9
- Molecular formula:
- C23H30O3
- IUPAC Name:
- (17β)-13-Ethyl-17-ethynyl-3-oxogon-4-en-17-yl acetate
Constituent 1
Results and discussion
In vivo (LLNA)
Results
- Parameter:
- EC3
- Value:
- 15.3
- Remarks on result:
- positive indication of skin sensitisation based on QSAR/QSPR prediction
Applicant's summary and conclusion
- Interpretation of results:
- Category 1B (indication of skin sensitising potential) based on GHS criteria
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