Registration Dossier
Registration Dossier
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EC number: 278-133-0 | CAS number: 75214-65-2
Endpoint summary
Administrative data
Description of key information
Acute aquatic hazard: not classified, according to the CLP Regulation (EC) No 1272/2008
Long-term aquatic hazard: Aquatic Chronic 2, H411, according to the CLP Regulation (EC) No 1272/2008
Additional information
Adequate chronic toxicity data is not available for Acid Black 222, thus the aquatic toxicity assessment and classification are based mainly on short-term toxicity data on the substance itself and on a structural analogue, Similar Substance 01. The read across approach can be considered as appropriate and suitable for the purpose. Details are available in section 13.
Although Acid Black 222 is neither readily nor inherently biodegradable, it has a logPow below 4 and low potential for bioaccumulation.
According to the CLP Regulation (EC) No 1272/2008, acute aquatic toxicity is normally determined using a fish 96-hour LC50 , a crustacean species 48 -hour EC50 and/or an algal species 72- or 96-hour EC50; the mentioned species cover a range of trophic levels and taxa and are considered as surrogate for all aquatic organisms. Data on other species (e.g.Lemna spp.) shall also be considered if the test methodology is suitable.
In the case of Acid Black 222 and analogue, data is available for fish (Poecilia reticulata and Danio rerio), invertebrates (Daphnia magna) and lemna (Lemna minor).
No L(E)C50 value was recorded at concentration equal/lower than 1 mg/l, thus the classification criteria for acute (short-term) aquatic hazard (category 1) of the CLP Regulation (EC) No 1272/2008 are not met.
Regarding the evaluation of the long-term aquatic hazard, the outcomes of tests performed on the three trophic levels suggest that fish is the most sensitive species, thus the classification is based on the short-term toxicity to this organism.
Available studies on short-term toxicity to fish showed EC50 values between 1 and 10 mg/l, thus the substance meets the criteria to be classified for long-term aquatic hazard, category 2 (i.e. Aquatic Chronic 2, H411), of the CLP Regulation (EC) No 1272/2008.
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