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EC number: 219-135-3 | CAS number: 2370-63-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Freshwater aquatic toxicity studies with ETMA were conducted in fish, invertebrates, and algal species.
Short-term toxicity to fish
In a 96-h acute toxicity study according to OECD Guideline 203, adopted 17 July 1992, Danio rerio (zebrafish) were exposed to ETMA at nominal concentrations of 0 (control), 6.25, 12.5, 25, 50 and 100 mg a.i./L under static renewal conditions.
The 96 h LC50 was 48.7 mg/L (based on nominal concentrations).
Short-term toxicity to aquatic invertebrates
The 48 h acute toxicity of ETMA to Daphnia magna was studied under static conditions according to OECD Guideline 202, adopted 4 April 1984 and EU Method C.2. Daphnids were exposed to control and test chemical at nominal concentration of 52.7, 79.0, 118.5, 177.8, 266.7, 400.0 mg/L for 48 h. Mortality/immobilisation was observed daily.
The 48 h EC50 based on measured initial concentrations was 170 mg/L (95% c.i. 130-230 mg/L).
Toxicity to aquatic algae
In a 72 hour toxicity study, the cultures of Pseudokirchneriella subcapitata CCAP 27814 were exposed to ETMA at nominal concentrations of 0 (control), 4.3, 9.4 20.7, 45.5, 100 and 200 mg/L under static conditions in accordance with OECD Guideline 201, adopted 07 June 1984, and EU test method C.3, 04 April 1992.
Microscopic observation showed that some algae exposed to the 2 highest concentrations appeared turgid in comparison to the control.
The EC10 and EC50 values based on growth rate were 22.0 mg/L and >184.2 mg/L, respectively. All effect levels are given based on initial measured concentrations of ETMA.
Toxicity to microorganisms
In a 3 h Respiration Inhibition Test according to OECD Guideline 209, adopted 22 July 2010, activated sludge obtained from a municipal treatment plant was exposed to ETMA at nominal concentrations of 10, 32, 100, 320 and 1000 mg/L under static conditions. In order to check the activity of the test system and the test conditions a reference test was carried out with copper (II) sulphate pentahydrate as reference item. The reference item produced the appropriate response.
The EC10 of ETMA based on respiration inhibition of activated sludge is 72.8 mg/L.
In conclusion, the lowest aquatic toxicity value for ETMA was the 96 h LC50 of 48.7 mg/L, based on the short-term toxicity study in Danio rerio.
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