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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-[bis(4-fluorophenyl)methyl]piperazine
EC Number:
248-476-0
EC Name:
1-[bis(4-fluorophenyl)methyl]piperazine
Cas Number:
27469-60-9
Molecular formula:
C17H18F2N2
IUPAC Name:
1-[bis(4-fluorophenyl)methyl]piperazine
Test material form:
solid: particulate/powder
Details on test material:
White to light yellow powder

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
methanol
Solubility:
> 50 other: g/100 mL solution
Medium:
ethanol
Solubility:
> 50 other: g/100 mL solution
Medium:
isopropanol
Solubility:
> 50 other: g/100 mL solution
Medium:
other: dichloromethane
Solubility:
> 50 other: g/100 mL solution
Medium:
other: 2-propanone
Solubility:
> 50 other: g/100 mL solution
Medium:
other: 1,1'-oxybisethane
Solubility:
35.5 other: g/100 mL solution
Medium:
other: methylbenzene
Solubility:
46.6 other: g/100 mL solution
Medium:
other: 4-methyl-2-pentatone
Solubility:
36.9 other: g/100 mL solution
Medium:
other: 2-butanone
Solubility:
> 50 other: g/100 mL solution
Medium:
other: 2,2'-oxybispropane
Solubility:
22.9 other: g/100 mL solution
Details on results:
no data

Any other information on results incl. tables

Table 1 Solubility of the substance T000841.

 Solvent  Solubility in g/100 mL solution

  Solubility at room temperature (Condition 1)

 N,N-dimethylformamide  >50

Solubility at 20 deg C (Condition 10)

 N,N-dimethylacetamide  > 20

Applicant's summary and conclusion