Registration Dossier
Registration Dossier
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EC number: 202-711-3 | CAS number: 98-89-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 1986
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The data obtained from a source of secondary literature are related to a substance which shows the same functional groups . The data derived from read-across is considered reliable because the molecules have the same functional groups due to the action irritating.
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
- Species:
- rabbit
- Strain:
- not specified
- Type of coverage:
- not specified
- Controls:
- not specified
- Irritation parameter:
- other: REACTION: Severe
- Irritant / corrosive response data:
- REACTION: Severe
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance is classified for this property.
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance is classified as irritant.
Justification for selection of skin irritation / corrosion endpoint:
The data obtained from a source of secondary literature are related to a substance which shows the same functional groups . The data derived from read-across is considered reliable because the molecules have the same functional groups due to the action irritating.
Effects on skin irritation/corrosion: irritating
Justification for classification or non-classification
According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance is classified as irritant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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