Registration Dossier

Administrative data

Endpoint:
skin irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chlorothioxanthen-9-one
EC Number:
201-667-2
EC Name:
2-chlorothioxanthen-9-one
Cas Number:
86-39-5
Molecular formula:
C13H7ClOS
IUPAC Name:
2-chloro-9H-thioxanthen-9-one

Results and discussion

In vitro

Results
Irritation / corrosion parameter:
other: other: Cell viability
Value:
ca. 89.3
Remarks on result:
other:
Remarks:
Time point: -. Remarks: Cell viability is above 50% and the test item is therefore not irritant.. (migrated information)

In vivo

Irritant / corrosive response data:
-

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: OECD GHS
Conclusions:
In conclusion, in this in vitro EPISKIN model test with the test item, the results indicate that the test item is not irritant to skin.