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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
thermal stability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13 October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 113 (Screening Test for Thermal Stability and Stability in Air)
Version / remarks:
1981
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Adenosine
EC Number:
200-389-9
EC Name:
Adenosine
Cas Number:
58-61-7
Molecular formula:
C10H13N5O4
IUPAC Name:
adenosine
impurity 1
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
Oxidane
Test material form:
solid: particulate/powder
Details on test material:
Batch No.: 10004539
Storage at room temperature approx. 20°C

Results and discussion

For thermal stability study

Test substance thermally stable:
yes
Operating temperatureopen allclose all
Key result
Operating temp.:
>= 220 - <= 250 °C
Remarks on result:
other: endothermic effect
Key result
Operating temp.:
>= 250 - <= 300 °C
Remarks on result:
other: exothermic effect
Sublimation:
not determined
Transformation products:
not specified

Any other information on results incl. tables

In the temperature range of 220 – 250 °C an endothermic effect can be observed, which is directly followed by an exothermic effect in the temperature range of 250 – 300 °C, with an average decomposition energy of -360 J/g. No further thermal effects could be observed up to the maximum test temperature of 500 °C.

Applicant's summary and conclusion

Conclusions:
The test item Adenosine (CAS no. 58-61-7) showed an endothermic effect in the temperature range of 220 – 250 °C, which is directly followed by a exothermic effect in the temperature range of 250 – 300 °C, with an average decomposition energy of -360 J/g.
Executive summary:

The test item Adenosine (CAS no. 58-61-7) showed an endothermic effect in the temperature range of 220 – 250 °C, which is directly followed by a exothermic effect in the temperature range of 250 – 300 °C, with an average decomposition energy of -360 J/g.