1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Water solubility:

0.653 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

1 g/L

Incubation duration:

24 h

Temp.:

20 °C

pH:

9.8

Details on results:

The water solubility of the test item has been determined to be 0.653 g/L of solution at 20.0 ± 0.5 °C, calculated using the total peak area of all detected components within the test item and a standardized initial
nominal saturation loading rate concentration of 1.00 g/L. As the test item was a complex mixture, the evaluation of water solubility also included an assessment of the influence of loading rate.
Information from the Sponsor indicating at least 20 discrete species identified by gas chromatography mass spectrometry (GC-MS) analysis.
Of the identified species, all but diethylenetriamine (1.66%) presented aromatic functional groups and hence the decision to detect the test item by UV absorbance at 270 nm.
Calculation of equivalent test item concentrations have therefore been performed based on the total peak area of all components detected although individual components demonstrated
differing solubility characteristics with later eluting, higher partition coefficient and therefore more hydrophobic species showing reduced solubility at all loading rates.

Conclusions:

Water Solubility of 1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether was determined to be 0.653 g/L at 20.0 ± 0.5 °C, calculated using the total peak area of all detected components within the test item and a standardized initial nominal saturation loading rate concentration of 1.00 g/L.

Executive summary:

Water Solubility of 1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether was determined to be 0.653 g/L  at 20.0 ± 0.5 °C, calculated using the total peak area of all detected components within the test item and a standardized initial nominal saturation loading rate concentration of 1.00 g/L.

Description of key information

Water Solubility of 1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether was determined to be 0.653 g/L  at 20.0 ± 0.5 °C, calculated using the total peak area of all detected components within the test item and a standardized initial nominal saturation loading rate concentration of 1.00 g/L.

Key value for chemical safety assessment

Water solubility:

0.653 g/L

at the temperature of:

20 °C