Registration Dossier
Registration Dossier
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EC number: 245-396-8 | CAS number: 23047-25-8
Endpoint summary
Administrative data
Description of key information
Overdose in humans may be associated with tachycardia, hypertension, dry mouth, dilated pupils, ileus, blurred vision, dizziness, flushing, hypersalivation, muscle weakness, and vomiting. Only 1 of 55 cases studied had deep coma requiring ventilation. Hypotension, convulsion, and cardiac arrhythmias were not reported.
Twenty-one patients ingested between 0.14 and 4.9 g. Seven were asymptomatic (mean dose 1.85 g) and 14 patients had mild symptoms. One had a deep coma, suffered from respiration depression, and required ventilation for 36 hours. Five had mild hypertension, 5 had tachycardia, and several had anticholinergic symptoms. Hypotension, convulsion, and cardiac arrhythmias were not reported. Ingestion with other drugs, hypotension, arrhythmias, and coma were observed.
Overall, the substance should be classified as H370 and H336.
Additional information
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