Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation: in vivo (LLNA)
Type of information:
other: read across based on OECD Toolbox v3.4
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
see attached OECD Toolbox study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Guideline:
OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
GLP compliance:
not specified
Type of study:
mouse local lymph node assay (LLNA)

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(butoxymethyl)methacrylamide
EC Number:
225-929-0
EC Name:
N-(butoxymethyl)methacrylamide
Cas Number:
5153-77-5
Molecular formula:
C9H17NO2
IUPAC Name:
N-(butoxymethyl)methacrylamide
Test material form:
liquid

In vivo test system

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Results and discussion

In vivo (LLNA)

Results
Key result
Parameter:
SI
Remarks on result:
other: no data

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU