Registration Dossier

Administrative data

Description of key information

No biologically significant signs of toxicity were observed.

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
NOAEL
1 000 mg/kg bw/day
Study duration:
subacute
Species:
rat

Repeated dose toxicity: inhalation - systemic effects

Endpoint conclusion
Endpoint conclusion:
no study available

Repeated dose toxicity: inhalation - local effects

Endpoint conclusion
Endpoint conclusion:
no study available

Repeated dose toxicity: dermal - systemic effects

Endpoint conclusion
Endpoint conclusion:
no study available

Repeated dose toxicity: dermal - local effects

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

The combined repeated dose toxicity study with reproduction/developmental toxicity study did not reveal any adverse effects associated with administration of the test substance. The NOAEL (No Observed Adverse Effect Level) for REPEATED DOSE TOXICITY in MALES and FEMALES was established as 1000 mg/kg/day body weight/day.