Registration Dossier

Administrative data

First-aid measures

Description of first aid measures
· General information:
Immediately remove any clothing soiled by the product.
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
Remove breathing equipment only after contaminated clothing have been completely removed.
Take note of the following instructions:
· After inhalation:
Supply fresh air or oxygen; call for doctor.
In case of unconsciousness place patient stably in the recovery position for transportation.
· After skin contact:
Immediately wash with water and soap and rinse thoroughly.
If skin irritation occurs, consult a doctor.
· After eye contact:
Rinse opened eye for several minutes under running water. Then consult a doctor.
· After swallowing: Do not induce vomiting; call for medical help immediately.

· Most important symptoms and effects, both acute and delayed: No further relevant information available.
· Indication of any immediate medical attention and special treatment needed: No further relevant information available.

Fire-fighting measures

· Extinguishing media
· Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· For safety reasons unsuitable extinguishing agents: Water with full jet

· Special hazards arising from the substance or mixture
Can form explosive gas-air mixtures.
Carbon monoxide and carbon dioxide

· Advice for firefighters
· Protective equipment:
Mount respiratory protective device.
Wear personal protective equipment.
· Additional information
Cool endangered container(s) with water spray.
Heating of container(s) will cause pressure rise with risk of bursting and subsequent explosion (BLEVE).
Dispose of fire debris and contaminated fire fighting water in accordance with official regulations.

Accidental release measures

· Personal precautions, protective equipment and emergency procedures
Wear personal protective equipment. Keep unprotected persons away.
Mount respiratory protective device.
Keep away from ignition sources.

· Environmental precautions:
Inform respective authorities in case of seepage into water course or sewage system.
Do not allow to enter sewers/ surface or ground water.
Suppress gases/fumes/haze with water spray.

· Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Clean the affected area carefully; suitable cleaners are:
Warm water
Ensure adequate ventilation.
Dispose contaminated material as waste according to specifications.

Handling and storage

· Precautions for safe handling
Keep away from heat and direct sunlight.
Handle under dry protective gas.
Prevent static electric sparks.
Ensure good ventilation/exhaustion at the workplace.
Open and handle receptacle with care.
Prevent formation of aerosols.
· Information about fire - and explosion protection:
Protect against electrostatic charges.
Protect from heat.
Traces of flammable substances may collect in the steam chamber of enclosed systems. Keep clear of ignition sources.
Fumes can combine with air to form an explosive mixture.
Heating of container(s) will cause pressure rise with risk of bursting and subsequent explosion (BLEVE).
The vapour may be invisible and is heavier than air. It spreads along the ground and may enter sewers and basements.

· Conditions for safe storage, including any incompatibilities
· Storage:
· Requirements to be met by storerooms and receptacles: Store in a cool location.
· Information about storage in one common storage facility: Store away from foodstuffs.
· Further information about storage conditions:
Keep container tightly sealed.
Store in cool, dry conditions in well sealed receptacles.
· Recommended storage temperature: +15 °C - +25 °C

· Specific end use(s) No further relevant information available.

Transport information

Land transport (ADR/RID)

UN number:
2056
Proper shipping name and description:
2056 TETRAHYDROFURAN
Chemical name:
TETRAHYDROFURAN
Class:
3
Classification code:
(F1) Flammable liquids
Labels:
3
Remarks:
· Excepted quantities (EQ): E2
· Limited quantities (LQ): 1L
· Excepted quantities (EQ) Code: E2
Maximum net quantity per inner packaging: 30 ml
Maximum net quantity per outer packaging: 500 ml
· Transport category: 2
· Tunnel restriction code: D/E

Inland waterway transport (ADN(R))

Shippingopen allclose all
Packaging group:
II
Remarksopen allclose all

Marine transport (IMDG)

UN number:
2056
Proper shipping name and description:
TETRAHYDROFURAN
Chemical name:
TETRAHYDROFURAN
Class:
3 Flammable liquids
Packaging group:
II
EmS code:
F-E,S-D
Labels:
3
Remarks
Limited quantities (LQ): 1L
· Excepted quantities (EQ) Code: E2
Maximum net quantity per inner packaging: 30 ml
Maximum net quantity per outer packaging: 500 ml

Air transport ICAO/IATA

UN number:
2056
Proper shipping name and description:
TETRAHYDROFURAN
Chemical name:
TETRAHYDROFURAN
Class:
3 Flammable liquids
Packaging group:
II
Labels:
3
Remarks
UN No. 2056
Special provisions: -
Danger Code: 3H
UN packing group: II
PASSENGER AND CARGO AIRCRAFT:
Excepted Quantities: E2
Packing instruction: 353
max. net quantity per package: 5 L
Limited Quantity:
Packing instruction: Y341
max. net quantity per package: 1 L
CARGO AIRCRAFT:
Packing instruction: 364
max. net quantity per package: 60 L
GRACE recommends CARGO AIRCRAFT only.
SpecialProvisionsopen allclose all

Exposure controls / personal protection

· Additional information about design of technical facilities: No further data

· Ingredients with limit values that require monitoring at the workplace: 109-99-9 tetrahydrofuran
WEL (Great Britain) Short-term value: 300 mg/m³, 100 ppm
Long-term value: 150 mg/m³, 50 ppm
Sk
IOELV (European Union) Short-term value: 300 mg/m³, 100 ppm
Long-term value: 150 mg/m³, 50 ppm
Skin

· DNELs (109-99-9 tetrahydrofuran):
Oral DNEL(long-systemic) 15 mg/kg bw /day (General population), ECHA 2011
Dermal DNEL(long-systemic) 15 mg/kg bw /day (General population), ECHA 2011
25 mg/kg bw /day (Worker), ECHA 2011
Inhalative DNEL(acute-systemic) 150 mg/m³ (General population), ECHA 2011
300 mg/m³ (Worker), ECHA 2011
DNEL(long-systemic) 62 mg/m³ (General population), ECHA 2011
150 mg/m³ (Worker), ECHA 2011
DNEL(acute-local) 300 mg/m³ (Worker), ECHA 2011
DNEL(long-local) 75 mg/m³ (General population), ECHA 2011
150 mg/m³ (Worker), ECHA 2011

· PNECs (109-99-9 tetrahydrofuran)
67 mg/kg (O), ECHA 2011
23.3 mg/kg (sediment (freshwater)), ECHA 2011
4.32 mg/l (aqua-freshwater), ECHA 2011
432 mg/l (aqua-marine water), ECHA 2011
4.6 mg/l (Sewage Treatment Plant), ECHA 2011

Additional information: Valid lists at time of creation were used as basis.

· Exposure controls
· Personal protective equipment:
· General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the eyes.
Avoid contact with the eyes and skin.
· Respiratory protection:
If the WEL value is exceeded.
Filter P3
· Protection of hands:
Protective gloves.
Check the condition of the gloves prior to each use.
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation.
Preventive skin protection by use of skin-protecting agents is recommended.
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Butyl rubber, BR
Nitrile rubber, NBR
Recommended thickness of the material: >= 0.7 mm
· Penetration time of glove material
EN 420: Minimum requirements for efficiency level 1 for all groups.
The exact break through time has to be obtained from the manufacturer of the protective gloves and has to be observed.
For the mixture of chemicals mentioned below the penetration time has to be at least 480 minutes (Permeation according to EN 374 Part 3: Level 6).
· For the permanent contact gloves made of the following materials are suitable:
Fluorocarbon rubber (Viton)
Nitrile rubber, NBR
· Not suitable are gloves made of the following materials:
Rubber gloves
Leather gloves
cloth gloves
· Eye protection:
Tightly sealed goggles
· Body protection: Protective work clothing.

Stability and reactivity

· 10.1 Reactivity: No further relevant information available.
· 10.2 Chemical stability:
No decomposition if used according to specifications.
No decomposition if used and stored according to specifications.
· Possibility of hazardous reactions:
Possible formation of peroxide.
Forms explosive gas mixture with air.
· Conditions to avoid
In case of thermal decomposition caused by smouldering and incomplete combustion toxic fumes may be developed.
· Incompatible materials: Protect from contamination.
· Hazardous decomposition products: Carbon monoxide and carbon dioxide

Disposal considerations

· Waste treatment methods
· Recommendation: Disposal must be made according to official regulations.
· Waste disposal key:
The disposal of the product has to be carried out in accordance with the legal requirements. EWC waste codes are strictly industry-oriented, therefore waste classification has to be done by the waste producer.
· Uncleaned packaging:
· Recommendation: Disposal must be made according to official regulations.