Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Gene Mutation in Bacteria -not mutagenic (OECD TG 471)

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

The mutagenic potential of Tetrakis (2-ethylbutyl) Orthosilicate has been evaluated based on data from an in-vitro bacterial mutagenicity assay. Mutagenic properties have not been demonstrated and classification is not warranted.

Justification for classification or non-classification

Tetrakis (2-ethylbutyl) Orthosilicate is not mutagenic in Salmonella typhimurium or Escherichia coli bacteria. This finding does not warrant classification of Tetrakis (2-ethylbutyl) Orthosilicate as a mutagen under the Regulation (EC) 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP).