Registration Dossier
Registration Dossier
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EC number: 231-744-6 | CAS number: 7718-98-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- CICAD 29: Vanadium pentoxide and other inorganic vanadium compounds
- Author:
- Dr M. Costigan, Mr R. Cary, Dr S. Dobson
- Year:
- 2 001
- Bibliographic source:
- World Health Organization
- Reference Type:
- secondary source
- Title:
- Effect on Organism of Vanadium Trioxide
- Author:
- IV Roshchin , AV Il'nitskaya , LA Lutsenko , LV Zhidkova
- Year:
- 1 965
- Bibliographic source:
- Fed. Proc. Transl. Suppl. 24, 611
Materials and methods
- Principles of method if other than guideline:
- No details
- GLP compliance:
- no
Test material
- Reference substance name:
- Vanadium trichloride
- EC Number:
- 231-744-6
- EC Name:
- Vanadium trichloride
- Cas Number:
- 7718-98-1
- Molecular formula:
- Cl3V
- IUPAC Name:
- vanadium trichloride
- Details on test material:
- No details
Constituent 1
- Specific details on test material used for the study:
- No details
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No details
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- No details
- Doses:
- No details
- No. of animals per sex per dose:
- No details
- Control animals:
- not specified
- Details on study design:
- No details
Results and discussion
- Preliminary study:
- No details
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 23 mg/kg bw
- Based on:
- element
- Remarks:
- Vanadium
- Mortality:
- No details
- Clinical signs:
- No details
- Body weight:
- No details
- Gross pathology:
- No details
- Other findings:
- No details
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- The articles review cite a mouse oral LD50 value around 23 mg/kg body weight (as vanadium) for vanadium chloride. No further details are available.
- Executive summary:
The articles review cite a mouse oral LD50 value around 23 mg/kg body weight (as vanadium) for vanadium chloride. No further details are available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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