Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 2017 - November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
other: metal block method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Specific details on test material used for the study:
Batch number: 80100005
Expiration date: 13 October 2018
Purity: 99.8%
Stored at Room temperature (nominally 15 to 25°C), dark
Physical state/appearance: White solid

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
> 62 - < 64 °C

Any other information on results incl. tables

 

Table 1. Metal block method results

Temperature

 Melting stage (as referenced in OECD Method 102)

 Sample I  Sample II
A  
B  
C  61.5 62.0 
 63.0 63.0 
E  64.0

64.0

The initial stages of melting, as referenced in OECD Method 102, were indistinct.

Differential scanning calorimetry (DSC)

The DSC trace showed a sharp endotherm at approximately 64°C, consistent with the melting temperature observed in the metal block test.

Applicant's summary and conclusion

Conclusions:
The melting range of WS-23 was found to be 62 to 64°C.
Executive summary:

The melting temperature of WS-23 was determined using the metal block method (according to OECD TG 102). The melting range of WS-23 was found to be 62 to 64°C.