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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15-Sep-2014 to 20-Sep-2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Remarks:
Staatliches Gewerbeaufsichtsamt Hildeshelm
Type of method:
flask method
Key result
Water solubility:
3.89 g/L
Temp.:
20 °C
pH:
6.7

Results

Preliminary Test (non GLP)

The determined solubility was in the range of 4.7 g/L. The samples were checked negative for Tyndall-effects. For the application dose of the definitive study, 50 g/L, as approx. the tenfold of the solubility result was used.

Main test

Water solubility results at 20 °C for the test item

Pre-incubation time

Replicate No.

Concentration1) (g/L)

Mean

24 h

1

3.72

3.75

2

3.77

48 h

1

3.86

3.90

2

3.93

72 h

1

3.99

4.02

2

4.05

Mean (24 – 72 h)

 

 

3.89

Deviation (%)2)

 

 

7

 

1) Mean values of two injections

2) Calculated according to the formula

The water solubility of Indoflor was determined to be: 3.89 g/L (20 °C, pH 6.7)

 

Conclusions:
A water solubility value of 3.89 g/L (at 20 °C, pH 6.7) was determined for the test substance according to E.U. Method A.6.

Description of key information

Water solubility: 3.89 g/L at 20 °C, pH = 6.7 (EU Method A.6,flask method)

Key value for chemical safety assessment

Water solubility:
3.89 g/L
at the temperature of:
20 °C

Additional information