Registration Dossier

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19 January to 29 March 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
GLP compliance:
no
Type of method:
effusion method: Knudsen cell
Temp.:
20 °C
Vapour pressure:
0.16 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0.26 Pa
Temp.:
50 °C
Vapour pressure:
2.5 Pa

Thermal stability test results

In the temperature range of 70 - 90 °C an endothermic effect (melting), was observed. No further thermal effects were observed up to the maximum test temperature of 300 °C.

 

Vapour pressure test results

The vapour pressure was measured in the temperature range of 20 to 46 °C. The measured vapour pressure values together with the measured temperatures are listed in the following table.

 

No.

Temperature / °C

Vapour pressure / Pa

1

20

0.175

2

25

0.251

3

30

0.394

4

35

0.708

5

41

1.130

6

46

1.760

 

The measured vapour pressure is slightly outside the measuring range (0.001 to 1 Pa) of the Knudsen cell. Nevertheless, as the vapour pressure value above 1 Pa could be detected properly by the Knudsen cell, this value can be used for the evaluation.

From the measured data points of the vapour pressure curve the constants A and B of the Antoine equation can be derived by regression of the data points:

 

A = 12.1567

B = -3800.43

 

The vapour pressure values of the test item calculated by interpolation and extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC No. 440/2008 Method A.4. Vapour Pressure and OECD Test Guideline 104 (2006) are shown in the table below.

 

Calculated vapour pressure values for 20, 25 and 50 °C

Temperature / °C

Vapour pressure / Pa

20

0.16

25

0.26

50

2.5

 

 

Final Results

The vapour pressure of the test item was calculated by interpolation and extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC No. 440/2008 Method A.4. Vapour Pressure and OECD Test Guideline 104 (2006). The resulting vapour pressures are 0.16, 0.26 and 2.5 Pa, respectively.

Conclusions:
Vapour pressure values of 0.16 Pa (at 20 °C), 0.26 Pa (at 25 °C) and 2.5 Pa (at 50 °C) were determined for the test substance according to E.U. Method A.4.

Description of key information

Vapour pressure: 0.16 Pa at 20 °C, 0.26 Pa at 25 °C, and 2.5 Pa at 50 °C (EU Method A.4, effusion method: Knudsen cell)

Key value for chemical safety assessment

Vapour pressure:
0.26 Pa
at the temperature of:
25 °C

Additional information

According to Regulation EC No. 440/2008 Method A.4, the vapour pressure values of the test item for the temperatures 20, 25 and 50 °C were calculated by extrapolation.