Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
GLP compliance:
not specified
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
impurity
Type:
impurity
Test material form:
solid: bulk
Details on test material:
This composition is the usual techical grade of AlzChem AG. It will be used when test substance has this composition (or is very closed) or no specific information is available
Specific details on test material used for the study:
Batch: 717841

Results and discussion

Boiling point
Key result
Atm. press.:
ca. 1 013 hPa
Decomposition:
yes
Decomp. temp.:
> 286 °C

Applicant's summary and conclusion

Conclusions:
Alpha-Lipoic acid decomposes at T > 286 °C
Executive summary:

The boiling temperature from a-Lipoic acid is measured by Differential-Scanning-Calorimetry. The test is according to EG 440/2008 A.2. The exakt boiling point at normal pressure for this substance is not avalible, it decomposes at temeratures T > 286 °C.