Reaction product of resin acid and rosin acid, 12-Hydroxyoctadecanoic and stearic acid with dipentaerythritol

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

27. Jan. - 16. Feb. 1998

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 7-7-B
- Expiration date of the lot/batch: 1. August 1999
- Purity test date: not stated

RADIOLABELLING INFORMATION (if applicable)
not applicable

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Stability under test conditions: assumed stable
- Solubility and stability of the test substance in the solvent/vehicle: assumed stable
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: not applicable

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
none

Key result

Water solubility:

ca. 0.3 mg/L

Conc. based on:

test mat.

Loading of aqueous phase:

1 000 mg/L

Incubation duration:

>= 24 - <= 72 h

Temp.:

20 °C

Remarks on result:

other: pH not stated

Conclusions:

In conclusion, the water solubility of DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/
STEARATE/ROSINATE at 20 °C ± 1.0 °C was determined to be about 0.3 mg/I ± 0.1 mg/I

Executive summary:

The determination of the water solubility of DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/

STEARATE/ROSINATE was perfarmed according to the EEC Directive 92/69,

A.6 ”Water Solubility'' (1992) and the OECD guideline No. 105, ” Water Solubility" (1995)

using the flask shake method.

The saturation concentration of DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/

STEARATE/ROSINATE at room temperature was estimated by a simplified flask method in

the preliminary test to be below 10-2 g/l. Nevertheless, the column elution method could not

be performed because of the pasty consistency of the test article and the difficulty to analyse

the test article with a chromatographic system.

The results of the individual measurements of the flask shaking test are summarised in table

2. The quantification was performed using a TOC analyzer. The amount of test article present

was calculated based on the molecular formula and the carbon content of the test article. The

concentrations determined after 24 hours and 72 hours differ by more than 15 %. This limit

usually applies to concentrations above 10 mg/I. Therefore a difference of about 22 %

between the 24 hours value and the 72 hours value is considered to be valid.

Description of key information

one guiedeline study available

Key value for chemical safety assessment

Water solubility:

0.3 mg/L

at the temperature of:

20 °C