Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

acute toxicity: inhalation
Data waiving:
other justification
Justification for data waiving:
Reason / purpose for cross-reference:
data waiving: supporting information
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From May 20, 2016 to June 03, 2016
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 104 (Vapour Pressure Curve)
according to guideline
EU Method A.4 (Vapour Pressure)
GLP compliance:
not specified
Type of method:
static method
Specific details on test material used for the study:
Batch No.: #120039110
purity: >95% (Composition: >95% Butyl carbamate; <5% n-Butanol)
Key result
20 °C
Vapour pressure:
265 Pa
Key result
25 °C
Vapour pressure:
328 Pa

Calculation of results:

From the measured values for the increasing and for the decreasing temperature, log P (in log Pa) and 1/T (in 1/K) were calculated. The measured and the calculated values were plotted (p against T and log P against 1/T). The regression curve with slope B, intercept A and correlation r was calculated (graph log P vs. 1/T). From the values of these parameters, vapour pressures at 20.0 and at 25.0 °C were calculated using the following equation:

log P = B*(1/T)+A,

P (20°C) = 10E(B*(1/293.15)+A) and P (25°C) = 10E(B*(1/298.15)+A).

Under the study conditions, the vapour pressure of the test substance was determined to be 265 and 328 Pa at 20 and 25°C, respectively.
Executive summary:

A study was conducted to determine the vapour pressure of the test substance, according OECD guideline 104 and EU Method A.4 (static method). 12 pairs temperature and vapour pressure were used to calculate a regression from which vapour pressure at ambient temperature was estimated. From the measured values, the vapour pressure of the test substance was calculated to be 265 Pa at 20.0 °C, and 328 Pa at 25 °C. The values of the heating and cooling down phase showed good correspondence (Krebs, 2016).

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion