Registration Dossier

Physical & Chemical properties

Surface tension

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2000-10-10
Reliability:
1 (reliable without restriction)
Qualifier:
according to
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Version / remarks:
OECD Guideline No. 115 (1995)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.5 (Surface Tension)
Version / remarks:
EEC Commission Directive 92/69 - A5 method ( 1992)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
ring method
Key result
Surface tension:
63.1 mN/m
Temp.:
20 °C
Conc.:
228.6 mg/L




Test item:


Surface tension of the test item (uncorrected value):


Assay No. 1: 66.2 mN/m at 20.1 °C


Assay No. 2: 66.0 mN/m at 20.3 °C


Assay No. 3: 66.0 mN/m at 20.3 °C


Distilled water:


ϕo: 72.75 mN/m (surface tension of water at +20°C; value given in the literature),


ϕg: 75.48 mN/m (surface tension of sterilized for injection water at 20.1°C).


Calibration factor: ϕb = 0.964



 




















ASSAY



MEASUREMENT


(mN/m)



CORRECTION USING


(ϕb (mN/m)



CORRECTION


ACCORDING TO


HAWKINS & JORDAN


TABLE (mN/m)



1


2


3



66.2


66.0


66.0



 


63.7



 


63.1







TABLE: CORRECTION FOR MEASURED VALUES OF SURFACE TENSION


Applicable to aqueous solutions only: ϕb = 1 g/cm3











































Experimental value


mN/m


 



Calibration using riders



Calibration using water



60



55.2



59.1



62



57.2



61.3



64



59.2



63.4



66



61.2



65.5



68



63.2



67.7



70



65.2



69.9












































Experimental value


mN/m


 



Calibration using riders



Calibration using water



60



55.2



59.1



62



57.2



61.3



64



59.2



63.4



66



61.2



65.5



68



63.2



67.7



70



65.2



69.9



 

Conclusions:
The surface tension of the test item is 63.1 mN/m ± 0.1 mN/m at a concentration of 228.6 mg/L
Executive summary:



A study was conducted according to Directive 92/69/EEC Method A.5 and OECD Guideline No. 115 to determine the surface tension of an aqueous solution of the test item using the ring method. Therefore, a saturated solution at 90 % of the test substance in ultrapure water was prepared. Surface tension was determined at 20 °C. The surface tension of an aqueous solution the test item at 90 % saturation concentration (228.6 mg/L) was found to be 63.1 mN/m. As this value is higher than 60 mN/m, the test item is not classified as surface active substance.

Description of key information




The surface tension of the test item is 63.1 mN/m ± 0.1 mN/m at a concentration of 228.6 mg/L.


 

Key value for chemical safety assessment

Surface tension:
63.1
in mN/m at 20°C and concentration in mg/L:
228.6

Additional information



A study was conducted according to Directive 92/69/EEC Method A.5 and OECD Guideline No. 115 to determine the surface tension of an aqueous solution of the test item using the ring method. Therefore, a saturated solution at 90 % of the test substance in ultrapure water was prepared. Surface tension was determined at 20 °C. The surface tension of an aqueous solution the test item at 90 % saturation concentration (228.6 mg/L) was found to be 63.1 mN/m. As this value is higher than 60 mN/m, the test item is not classified as surface active substance.