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Physical & Chemical properties

Partition coefficient

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Description of key information

LogPow = 0.75 +/- 0.01 at 24°C and at pH 7.21

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
24 °C

Additional information

The partition coefficient (Pow) of the test item was estimated according to the A8 method and the OECD 117 (HPLC), and GLP.

HPLC was performed on a Nova-Pak C18 column packed with solid phase containing long hydrocarbon chains chemically bound onto silica. The test item was eluted along the column by partitioning between the mobile solvent phase and the hydrocarbon stationary phase. The test item injected in duplicate and was retained in proportion to its hydrocarbon-water partition coefficient. Reference items were chosen within the reference list of the OECD guideline 117. A relationship between the retention time on a reverse-phase column and the n-octanol/water partition coefficient was established. Result: LogPow = 0.75 +/- 0.01 at 24°C +/- 2°C at pH 7.21