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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
experimental data of read across substances
Justification for type of information:
Data for the target chemical is summarized based on the structurally similar read across chemicals
Reason / purpose:
read-across source
Reason / purpose:
read-across source
Reason / purpose:
read-across source
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
WoE report is based on two hydrolysis studies as-
1., 2. and 3.
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material (IUPAC name): (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene
- Common name: Isolongifolene
- Moleuclar formula: C15H24
- Molecular weight: 204.3546 g/mol
- Substance type: Organic
- Smiles: CC1(C)CCC=C2C(C)(C)[C@H]3CC[C@@]12C3
- Inchi: 1S/C15H24/c1-13(2)8-5-6-12-14(3,4)11-7-9-15(12,13)10-11/h6,11H,5,7-10H2,1-4H3/t11-,15-/m0/s1
- Physical state: liquid

Oxygen conditions:
other: 1. and 2. No data available, 3. aerobic
Inoculum or test system:
other: 1. and 2. No data available, 3. activated sludge (adaptation not specified)
Details on inoculum:
1. and 2. No data available

3. - Concentration of sludge: 30 mg/l
Duration of test (contact time):
28 d
Based on:
other: 1. Details not known
Initial conc.:
100 mg/L
Based on:
test mat.
Remarks:
2. and 3.
Parameter followed for biodegradation estimation:
O2 consumption
Remarks:
1.
Parameter followed for biodegradation estimation:
test mat. analysis
Remarks:
2. (%degradation)
Parameter followed for biodegradation estimation:
other: 3. BOD and GC
Details on study design:
1. and 2. No data available

3. Standard type
Parameter:
% degradation (O2 consumption)
Value:
74
Sampling time:
28 d
Remarks on result:
other: 1. Other details not known
Parameter:
% degradation (test mat. analysis)
Value:
59
Sampling time:
10 d
Remarks on result:
other: 2. Other details not known
Parameter:
% degradation (test mat. analysis)
Value:
67
Sampling time:
14 d
Remarks on result:
other: 2. Other details not known
Parameter:
% degradation (test mat. analysis)
Value:
75
Sampling time:
20 d
Remarks on result:
other: 2. Other details not known
Parameter:
% degradation (test mat. analysis)
Value:
83
Sampling time:
28 d
Remarks on result:
other: 2. Other details not known
Parameter:
other: BOD
Value:
94
Sampling time:
28 d
Remarks on result:
other: 3. Other details not known
Parameter:
other: GC
Value:
100
Sampling time:
28 d
Remarks on result:
other: 3. Other details not known
Details on results:
1. Test chemical undergoes 74% degradation by O2 consumption parameter in 28 days.
2. Test chemical undergoes 59, 67, 75 and 83% degradation by Test material analysis parameter in 10, 14, 20 and 28 days, respectively.
3. Test chemical undergoes 94% and 100% degradation by BOD and GC parameter in 28 days.
Validity criteria fulfilled:
not specified
Interpretation of results:
readily biodegradable
Conclusions:
On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the percentage degradation of the test chemical can be expected to be 74, 83, 94 and 100% by O2 consumption, test material analysis, BOD and GC parameter in total 28 days, respectively. Thus, based on this, it can be concluded that the test chemical is readily biodegradable in water.

Executive summary:

Data available for the test chemical has been reviewed to determine the percentage biodegradation. The studies are as mentioned below:

The percentage degradation of test chemical was determined to be 74% by O2 consumption parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in water.

In an another study, biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test chemical. The study was performed according to Council Directive 92/69/EEC Method C.4-D guidelines. Initial test substance conc. used in the study was 100 mg/l. The percentage degradation of test chemical was determined to be 59, 67, 75 and 83% by Test material analysis parameter in 10, 14, 20 and 28 days, respectively. Thus, based on percentage degradation,test chemical is considered to be readily biodegradable in nature.

Another biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test chemical. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test chemical was determined to be 94% and 100% by BOD and GC parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in nature.

On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the percentage degradation of the test chemical can be expected to be 74, 83, 94 and 100% by O2 consumption, test material analysis, BOD and GC parameter in total 28 days, respectively. Thus, based on this, it can be concluded that the test chemical is readily biodegradable in water.

Description of key information

On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the percentage degradation of the test chemical can be expected to be 74, 83, 94 and 100% by O2 consumption, test material analysis, BOD and GC parameter in total 28 days, respectively. Thus, based on this, it can be concluded that the test chemical is readily biodegradable in water.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

Data available for the test chemical has been reviewed to determine the percentage biodegradation. The studies are as mentioned below:

 

The percentage degradation of test chemical was determined to be 74% by O2 consumption parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in water.

 

In an another study, biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test chemical. The study was performed according to Council Directive 92/69/EEC Method C.4-D guidelines. Initial test substance conc. used in the study was 100 mg/l. The percentage degradation of test chemical was determined to be 59, 67, 75 and 83% by Test material analysis parameter in 10, 14, 20 and 28 days, respectively. Thus, based on percentage degradation,test chemical is considered to be readily biodegradable in nature.

 

Another biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test chemical. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test chemical was determined to be 94% and 100% by BOD and GC parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in nature.

 

On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the percentage degradation of the test chemical can be expected to be 74, 83, 94 and 100% by O2 consumption, test material analysis, BOD and GC parameter in total 28 days, respectively. Thus, based on this, it can be concluded that the test chemical is readily biodegradable in water.