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EC number: 947-037-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Remarks:
- Early study, but reporting the main relevant details, No GLP, short report
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
- Report date:
- 1974
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- no
- Remarks:
- pre-dates GLP
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Reaction mass of sodium sulphate and trisodium trioxalatoferrate
- EC Number:
- 947-037-7
- IUPAC Name:
- Reaction mass of sodium sulphate and trisodium trioxalatoferrate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: CFY strain
- Sex:
- male
- Details on test animals or test system and environmental conditions:
- no data
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- water
- Details on dermal exposure:
- TEST SITE
- Area of exposure: dorso-lumbar region
- Type of wrap if used: Al foil + waterproof plaster
REMOVAL OF TEST SUBSTANCE
- Washing (if done): with warm (40-50°C} dilute soap solution
- Time after start of exposure: 24 h
TEST MATERIAL
- Amount(s) applied (volume): 6,7 mL/kg
- Concentration: 75 % suspension
- Constant volume or concentration used: yes
- For solids, paste formed: yes - Duration of exposure:
- 24 h
- Doses:
- 5 000 mg/kg bw
- No. of animals per sex per dose:
- 10
- Control animals:
- yes, concurrent vehicle
Results and discussion
Effect levels
- Key result
- Sex:
- male
- Dose descriptor:
- LD0
- Effect level:
- >= 5 000 mg/kg bw
- Mortality:
- None
- Clinical signs:
- other: shortly after dosing slight lethargy. One rat showed slight erythema on the fourth day of treatment only. This rat and another were observed to have small, raised, brown nodules on areas on the treated sites on the day after treatment only
- Gross pathology:
- Autopsy findings were normal
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The acute median lethal percutaneous dose (LD 50 ) to male rats of the test item was found to be: greater than 5000 mg/kg bodyweight.
- Executive summary:
Ten male rats were treated with The test item at a dosage level of 5 g/kg bodyweight.
There were no mortalities. Signs of reaction to treatment, observed shortly after dosing, consisted of slight lethargy only, which persisted for three days. One rat showed slight erythema on the fourth day of treatment only. This rat and another were observed to have small, raised, brown nodules on areas on the treated sites on the day after treatment only. Bodyweight increases were normal compared with the controls. Autopsy findings were normal.
CONCLUSION: The acute median lethal percutaneous dose (LD 50 ) to male rats of gold 4 N was found to be: greater than 5000 mg/kg bodyweight.
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