Registration Dossier

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Adsorption to solid soil phase is not expected.

Key value for chemical safety assessment

Koc at 20 °C:

Additional information

The soil adsorption coefficient (Koc) was calculated using EPIsuite KOCWIN program. Using the molecular connectivity index (MCI) method the Koc was calculated to be 62 L/kg and log Koc to be 1.79 respectively. Using the Kow method the Koc was calculated to be 85.5 L/kg and Log Koc to be 1.93 respectively. The different calculation models show a good consistence. The calculated log Koc using the log Pow method was regarded as most reliable because this value was based on a measured log Pow of the substance. The Koc of 85.5 L/Kg was regarded as worst case assumption and therefore chosen as key value for chemical safety assessment (if required). Thus, adsorption to solid soil phase is not expected.

In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of 2-ethylimidazole (Q)SAR results were used for adsorption / desorption.The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment  (if required).  

Therefore, further experimental studies on adsorption / desorption are are not provided. 

[LogKoc: 1.93]