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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
explosiveness
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.14 (Explosive properties)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Escin
EC Number:
229-880-6
EC Name:
Escin
Cas Number:
6805-41-0
Molecular formula:
C110H172O48
IUPAC Name:
(2S,3S,4S,5R,6R)-6-{[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-9-(acetyloxy)-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(2-methylbutanoyl)oxy]-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-4-hydroxy-3,5-bis({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})oxane-2-carboxylic acid; (2S,3S,4S,5R,6R)-6-{[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-9-(acetyloxy)-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-{[(2E)-2-methylbut-2-enoyl]oxy}-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-4-hydroxy-3,5-bis({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})oxane-2-carboxylic acid
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Small-scale preliminary testsopen allclose all
Key result
Parameter:
thermal sensitivity - Koenen test: diameter of the orifice plate
Value:
6
Number of fragments:
0
Remarks on result:
not thermal sensitive if heated under defined confinement
Key result
Parameter:
sensitiveness to impact: impact energy (J)
Value:
40
Number of fragments:
0
Remarks on result:
not sensitive to impact using an impact energy of 40 J
Key result
Parameter:
sensitiveness to friction: friction load (N)
Value:
360
Number of fragments:
0
Remarks on result:
not sensitive to friction using a friction load of 360 N

Any other information on results incl. tables

Termal sensitivity (Effect of a FLAME):

Test with the 6.0 mm diameter orifice plate on Escin sample are described below:

- widening of the flame from around 36 seconds

- culmination phase from around 146 seconds with intense flame, white smokes and fire rain

- end of the culmination phase at around 202 seconds

- end of the observations after around 600 seconds

Tests with the 2.0 mm diameter orifice plate on the Escin sample gave the same results described above except for a more intense flame.

No one of the six test performed (three with the 6.0 mm orifice plate and three with the 2.0 orifice plate) produced the fragmentation of the steel tube containing the Escin sample.

Mechanical sensitivity (Shock)

Explosions did not occur (bursting into flame and/or a report is equivalent to explosion) in anyone of the six test performed with the impact energy of 40 J on a sample of escin sample.

Then the sample of Escin resulted not sensitive to shocking.

Mechanical sensibility (Friction)

Explosions did not pccur (crepitation and/or a report or bursting into flame are equivalent to explosion) in anyone of the six tests performed with with a loading of 360 N on a sample of escin. Then the sample of Escin resulted not sensitive to friction.

Applicant's summary and conclusion

Interpretation of results:
non explosive
Remarks:
Migrated information
Conclusions:
non explosive OBSOLETED